产品名称
YPEL5 Rabbit Polyclonal Antibody
蛋白名称
Protein yippee-like 5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51646
Human Swissprot No.
P62699
Human Swissprot Link
https://www.uniprot.org/uniprot/P62699
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=383295
Mouse Swissprot No.
P62700
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P62700/entry
特异性
This antibody detects endogenous levels of YPEL5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Midbody . Deteted in nucleus and at the centrosome during interphase. During mitosis, detected on the mitotic spindle, at spindle poles and at the midbody. .
功能
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 . Required for normal cell proliferation (By similarity).
