产品名称
ATP11B Rabbit Polyclonal Antibody
基因名称
ATP11B ATPIF ATPIR KIAA0956
蛋白名称
Probable phospholipid-transporting ATPase IF (EC 3.6.3.1) (ATPase IR) (ATPase class VI type 11B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23200
Human Swissprot No.
Q9Y2G3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y2G3
特异性
This antibody detects endogenous levels of ATP11B at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Recycling endosome membrane ; Multi-pass membrane protein. Early endosome . Endoplasmic reticulum . Golgi apparatus, trans-Golgi network . Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B (PubMed:21914794). In the presence of TMEM30A, mainly located in recycling endosomes (PubMed:21914794). .
功能
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes . May contribute to the maintenance of membrane lipid asymmetry in endosome compartment .
