产品名称
FAM46C Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54855
Human Swissprot No.
Q5VWP2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q5VWP2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74645
Mouse Swissprot No.
Q5SSF7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5SSF7/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=310721
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIV0/entry
特异性
This antibody detects endogenous levels of FAM46C at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Recruited into the centrosome through its interaction with PLK4. .
功能
Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression . Can also elongate RNA oligos ending with uridine molecule, provided that the sequence is adenosine-rich . Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein . ; (Microbial infection) Seems to enhance replication of some viruses, including yellow fever virus, in response to type I interferon.
