产品名称
VPS8 Rabbit Polyclonal Antibody
蛋白名称
Vacuolar protein sorting-associated protein 8 homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23355
Human Swissprot No.
Q8N3P4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8N3P4
Mouse Swissprot No.
Q0P5W1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q0P5W1/entry
特异性
This antibody detects endogenous levels of VPS8 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations . Functions predominantly in APPL1-containing endosomes .
