产品名称
SGLT3/SLC5A4 Rabbit Polyclonal Antibody
蛋白名称
Low affinity sodium-glucose cotransporter (Sodium/glucose cotransporter 3) (Na(+)/glucose cotransporter 3) (Solute carrier family 5 member 4)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6527
Human Swissprot No.
Q9NY91
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NY91
Mouse Swissprot No.
Q9ET37
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ET37/entry
特异性
This antibody detects endogenous levels of SGLT3/SLC5A4 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level) (PubMed:13130073). Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level) (PubMed:13130073). Detected in kidney (at protein level) (PubMed:22766068).
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
Has electrogenic activity in response to glucose, and may function as a glucose sensor . Mediates influx of sodium ions into the cell but does not transport sugars . Also potently activated by imino sugars such as deoxynojirimycin (DNJ) .
