产品名称
RAB1A Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-1A (YPT1-related protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P62820
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P62820/entry
Mouse Swissprot No.
P62821
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P62821
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q6NYB7
免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
RAB1A Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008],
组织表达
Brain,Colon,Placenta,Platelet,Tongue,
细胞定位
Golgi apparatus . Endoplasmic reticulum . Early endosome . Cytoplasm, cytosol . Membrane . Melanosome . Alternates between membrane-associated and cytosolic forms. .
功能
function:Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.,PTM:Phosphorylated by CDC2 kinase during mitosis.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:May interact with YIPF5.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
