产品名称
C7orf30 Rabbit Polyclonal Antibody
蛋白名称
Mitochondrial assembly of ribosomal large subunit protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=115416
Human Swissprot No.
Q96EH3
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96EH3
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=75593
Mouse Swissprot No.
Q9CWV0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWV0/entry
特异性
This antibody detects endogenous levels of C7orf30 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Mitochondrion matrix . Colocalizes with MRPL12 and/or MRPL14. .
功能
Required for normal mitochondrial ribosome function and mitochondrial translation . May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome . May function as a ribosomal silencing factor (Probable).
