产品名称
PMFBP1 Rabbit Polyclonal Antibody
蛋白名称
Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83449
Human Swissprot No.
Q8TBY8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TBY8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56523
Mouse Swissprot No.
Q9WVQ0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WVQ0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=171414
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z221/entry
特异性
This antibody detects endogenous levels of PMFBP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cell projection, cilium, flagellum . Localized at the sperm head-tail connecting piece (PubMed:30032984, PubMed:30298696). During spermatogenesis, it is first observed in the cytoplasm of round spermatids, it later appears in the implantation fossa region of the sperm nucleus during sperm head elongation and differentiation, and finally it localizes to the head-tail connecting piece (By similarity). .
功能
Required for normal spermatogenesis . It functions as a scaffold protein that attaches the sperm head-tail connecting piece to the nuclear envelope, thus maintaining sperm head and tail integrity . May also be involved in the general organization of cellular cytoskeleton (By similarity).
