产品名称
RAB17 Rabbit Polyclonal Antibody
蛋白名称
Ras-related protein Rab-17
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H0T7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H0T7/entry
Mouse Swissprot No.
P35292
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P35292
免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
RAB17 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009],
组织表达
Expressed in melanocytes (at protein level).
细胞定位
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cell projection, dendrite . May also localize at the basolateral and apical plasma membrane. In neurons, localizes to the cell body and dendritic shaft and spine. .
功能
function:Might be involved in transcellular transport.,similarity:Belongs to the small GTPase superfamily. Rab family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.