产品名称
MYOZ1 Rabbit Polyclonal Antibody
蛋白名称
Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58529
Human Swissprot No.
Q9NP98
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NP98
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59011
Mouse Swissprot No.
Q9JK37
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JK37/entry
特异性
This antibody detects endogenous levels of MYOZ1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas.
细胞定位
Nucleus. Cell projection, pseudopodium. Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle.
功能
Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
