产品名称
Syntenin 2 Rabbit Polyclonal Antibody
蛋白名称
Syntenin-2 (Syndecan-binding protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27111
Human Swissprot No.
Q9H190
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H190
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228765
Mouse Swissprot No.
Q99JZ0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99JZ0/entry
特异性
This antibody detects endogenous levels of Syntenin 2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Preferentially expressed in cells of the digestive tract (PubMed:11102519). Low expression in skeletal muscle and kidney (PubMed:11102519). Detected in differentiated keratinocytes of normal and malignant epithelium (PubMed:22623796). In healthy skin, expression is localized in suprabasal epidermal layers (PubMed:22623796).
细胞定位
Cytoplasm . Nucleus, nucleolus . Nucleus, nucleoplasm . Cell membrane . Nucleus speckle . Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments (PubMed:11102519). Colocalizes with TM4SF1 in the apical region of the cell (PubMed:11102519). Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments (PubMed:15961997). PIP2 plays an important role in the distribution of SDCBP2 (PubMed:23300061). .
功能
Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival .
