产品名称
LANCL1 Rabbit Polyclonal Antibody
蛋白名称
LanC-like protein 1 (40 kDa erythrocyte membrane protein) (p40)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10314
Human Swissprot No.
O43813
Human Swissprot Link
https://www.uniprot.org/uniprot/O43813
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14768
Mouse Swissprot No.
O89112
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O89112/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114515
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QX69/entry
特异性
This antibody detects endogenous levels of LANCL1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis.
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein .
功能
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism (By similarity). May play a role in EPS8 signaling. Binds glutathione .
