产品名称
RRAGD Rabbit Polyclonal Antibody
蛋白名称
Ras-related GTP-binding protein D (Rag D) (RagD)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NQL2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NQL2/entry
Mouse Swissprot No.
Q7TT45
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TT45
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
RRAGD Polyclonal Antibody detects endogenous levels of protein.
稀释度
IP 1:50-200 WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004],
细胞定位
Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .
功能
function:Has guanine nucleotide-binding activity but lacks intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.