产品名称
UCHL5 Rabbit Polyclonal Antibody
基因名称
UCHL5 UCH37 AD-019 CGI-70
蛋白名称
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51377
Human Swissprot No.
Q9Y5K5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y5K5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56207
Mouse Swissprot No.
Q9WUP7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WUP7/entry
特异性
This antibody detects endogenous levels of UCHL5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus.
功能
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1.