产品名称
DTX4 Rabbit Polyclonal Antibody
基因名称
DTX4 KIAA0937 RNF155
蛋白名称
E3 ubiquitin-protein ligase DTX4 (EC 6.3.2.-) (Protein deltex-4) (Deltex4) (RING finger protein 155)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23220
Human Swissprot No.
Q9Y2E6
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y2E6
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=207521
Mouse Swissprot No.
Q6PDK8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PDK8/entry
特异性
This antibody detects endogenous levels of DTX4 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
