产品名称
PES1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23481
Human Swissprot No.
O00541
Human Swissprot Link
https://www.uniprot.org/uniprot/O00541
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64934
Mouse Swissprot No.
Q9EQ61
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EQ61/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=289740
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q3B8N8/entry
特异性
This antibody detects endogenous levels of PES1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.
细胞定位
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli. .
功能
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
