产品名称
SNRPA Rabbit Polyclonal Antibody
蛋白名称
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6626
Human Swissprot No.
P09012
Human Swissprot Link
https://www.uniprot.org/uniprot/P09012
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=53607
Mouse Swissprot No.
Q62189
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q62189/entry
特异性
This antibody detects endogenous levels of SNRPA at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
