产品名称
ATP13A1 Rabbit Polyclonal Antibody
基因名称
ATP13A1 ATP13A KIAA1825 CGI-152
蛋白名称
Probable cation-transporting ATPase 13A1 (EC 3.6.3.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57130
Human Swissprot No.
Q9HD20
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9HD20
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170759
Mouse Swissprot No.
Q9EPE9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EPE9/entry
特异性
This antibody detects endogenous levels of ATP13A1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum . Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane . Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains .
