产品名称
SFXN1 Rabbit Polyclonal Antibody
蛋白名称
Sideroflexin-1 (Tricarboxylate carrier protein) (TCC)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94081
Human Swissprot No.
Q9H9B4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H9B4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14057
Mouse Swissprot No.
Q99JR1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99JR1/entry
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63965/entry
特异性
This antibody detects endogenous levels of SFXN1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in tissues with high one-carbon metabolism activity, such as blood, liver and kidney.
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
功能
Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway . Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors . Transports both D-serine and L-serine . Also able to transport other amino-acids, such as alanine . May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity).
