产品名称
ASUN Rabbit Polyclonal Antibody
蛋白名称
Protein asunder homolog (Cell cycle regulator Mat89Bb homolog) (Sarcoma antigen NY-SAR-95)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55726
Human Swissprot No.
Q9NVM9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NVM9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71177
Mouse Swissprot No.
Q8QZV7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8QZV7/entry
特异性
This antibody detects endogenous levels of ASUN at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
细胞定位
Nucleus . Cytoplasm . Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M. .
功能
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing .
