产品名称
WSB1 Rabbit Polyclonal Antibody
蛋白名称
WD repeat and SOCS box-containing protein 1 (WSB-1) (SOCS box-containing WD protein SWiP-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26118
Human Swissprot No.
Q9Y6I7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y6I7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78889
Mouse Swissprot No.
O54927
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O54927/entry
特异性
This antibody detects endogenous levels of WSB1 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
