产品名称
RIM1 Rabbit Polyclonal Antibody
基因名称
RIMS1 KIAA0340 RAB3IP2 RIM1 Nbla00761
蛋白名称
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22999
Human Swissprot No.
Q86UR5
Human Swissprot Link
https://www.uniprot.org/uniprot/Q86UR5
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116837
Mouse Swissprot No.
Q99NE5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99NE5/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84556
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JIR4/entry
特异性
This antibody detects endogenous levels of RIM1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in melanocytes (PubMed:23999003). Detected in brain and retina (PubMed:23999003).
细胞定位
Cell membrane ; Peripheral membrane protein . Cell junction, synapse . Cell junction, synapse, presynaptic cell membrane ; Peripheral membrane protein .
功能
Rab effector involved in exocytosis (By similarity). May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (By similarity). Plays a role in dendrite formation by melanocytes .
