产品名称
DNAJC7 Rabbit Polyclonal Antibody
蛋白名称
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7266
Human Swissprot No.
Q99615
Human Swissprot Link
https://www.uniprot.org/uniprot/Q99615
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56354
Mouse Swissprot No.
Q9QYI3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QYI3/entry
特异性
This antibody detects endogenous levels of DNAJC7 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . Cytoplasm, cytoskeleton . Colocalizes with NR1I3 to microtubules. .
功能
Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity).
