产品名称
RTN1 (Isoform RTN1-C) Rabbit Polyclonal Antibody
蛋白名称
Reticulon-1 (Neuroendocrine-specific protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6252
Human Swissprot No.
Q16799
Human Swissprot Link
https://www.uniprot.org/uniprot/Q16799
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104001
Mouse Swissprot No.
Q8K0T0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K0T0/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=116644
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q64548/entry
特异性
This antibody detects endogenous levels of RTN1 (Isoform RTN1-C) at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation.
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
功能
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity.
