产品名称
COSMC Rabbit Polyclonal Antibody
基因名称
C1GALT1C1 COSMC HSPC067 MSTP143 UNQ273/PRO310
蛋白名称
C1GALT1-specific chaperone 1 (C38H2-like protein 1) (C38H2-L1) (Core 1 beta1,3-galactosyltransferase 2) (C1Gal-T2) (C1GalT2) (Core 1 beta3-Gal-T2) (Core 1 beta3-galactosyltransferase-specific molecular chaperone)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29071
Human Swissprot No.
Q96EU7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96EU7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59048
Mouse Swissprot No.
Q9JMG2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JMG2/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=302499
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q499P3/entry
特异性
This antibody detects endogenous levels of COSMC at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitously expressed. Abundantly expressed in salivary gland, stomach, small intestine, kidney, and testis and at intermediate levels in whole brain, cerebellum, spinal cord, thymus, spleen, trachea, lung, pancreas, ovary, and uterus.
细胞定位
Membrane ; Single-pass type II membrane protein .
功能
Probable chaperone required for the generation of 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1).