产品名称
RASF3 Rabbit Polyclonal Antibody
蛋白名称
Ras association domain-containing protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q86WH2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86WH2/entry
Mouse Swissprot No.
Q99P51
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99P51
免疫原
Synthesized peptide derived from human protein . at AA range: 160-240
特异性
RASF3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Localized to microtubules in vascular endothelial cells.
功能
caution:Has been termed RASSF5 by Ref.1.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subcellular location:Localized to microtubules in vascular endothelial cells.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
