产品名称
DYNC2LI1 Rabbit Polyclonal Antibody
基因名称
DYNC2LI1 D2LIC LIC3 CGI-60
蛋白名称
Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51626
Human Swissprot No.
Q8TCX1
Human Swissprot Link
https://www.uniprot.org/uniprot/Q8TCX1
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=213575
Mouse Swissprot No.
Q8K0T2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K0T2/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=298767
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AY43/entry
特异性
This antibody detects endogenous levels of DYNC2LI1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in bone, brain, kidney, and cartilage (PubMed:26077881, PubMed:26130459). Lower expression in heart, liver, lung, placenta and thymus (PubMed:26077881).
细胞定位
Golgi apparatus . Cytoplasm . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes to the apical cytoplasm. .
功能
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles . Involved in the regulation of ciliary length .