产品名称
HPS4 Rabbit Polyclonal Antibody
蛋白名称
Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=89781
Human Swissprot No.
Q9NQG7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NQG7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=192232
Mouse Swissprot No.
Q99KG7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99KG7/entry
特异性
This antibody detects endogenous levels of HPS4 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 .
