产品名称
GDS1 Rabbit Polyclonal Antibody
蛋白名称
Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P52306
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P52306/entry
免疫原
Synthesized peptide derived from human protein . at AA range: 230-310
特异性
GDS1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The smg GDP dissociation stimulator (smgGDS) protein is a stimulatory GDP/GTP exchange protein with GTPase activity (Riess et al., 1993 [PubMed 8262526]).[supplied by OMIM, Feb 2010],
组织表达
Brain,Muscle,PCR rescued clones,Peripheral blood,
细胞定位
Cytoplasm, cytosol . Endoplasmic reticulum . Mitochondrion . Nucleus . Nuclear import is dependent on complexing with a GTPase containing a C-terminal polybasic region. .
功能
function:Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.,similarity:Contains 5 ARM repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
