产品名称
ZFYVE16 Rabbit Polyclonal Antibody
蛋白名称
Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9765
Human Swissprot No.
Q7Z3T8
Human Swissprot Link
https://www.uniprot.org/uniprot/Q7Z3T8
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=218441
Mouse Swissprot No.
Q80U44
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80U44/entry
特异性
This antibody detects endogenous levels of ZFYVE16 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes.
细胞定位
Cytoplasm . Early endosome membrane ; Peripheral membrane protein . Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P).
功能
May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.