产品名称
RANG Rabbit Polyclonal Antibody
蛋白名称
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P43487
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P43487/entry
Mouse Swissprot No.
P34022
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P34022
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
RANG Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
细胞定位
intracellular,nucleus,nuclear envelope,cytoplasm,centrosome,cell-cell adherens junction,axon cytoplasm,
功能
function:Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.,similarity:Belongs to the RANBP1 family.,similarity:Contains 1 RanBD1 domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
