产品名称
MYOT Rabbit Polyclonal Antibody
蛋白名称
Myotilin (57 kDa cytoskeletal protein) (Myofibrillar titin-like Ig domains protein) (Titin immunoglobulin domain protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9499
Human Swissprot No.
Q9UBF9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UBF9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58916
Mouse Swissprot No.
Q9JIF9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9JIF9/entry
特异性
This antibody detects endogenous levels of MYOT at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in skeletal muscle (at protein level). Expressed in skeletal muscle, heart, bone marrow and thyroid gland.
细胞定位
Cell membrane, sarcolemma . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Sarcomeric, also localized to the sarcolemma (PubMed:10369880). Colocalizes with MYOZ1 at the Z-lines in skeletal muscle (PubMed:16076904). .
功能
Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells.