产品名称
TMEM70 Rabbit Polyclonal Antibody
蛋白名称
Transmembrane protein 70, mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54968
Human Swissprot No.
Q9BUB7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BUB7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70397
Mouse Swissprot No.
Q921N7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q921N7/entry
特异性
This antibody detects endogenous levels of TMEM70 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Lower expressed in the heart than in the liver (at protein level).
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein . Mostly located within the inner cristae membrane. .
功能
Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction . Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis . In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies .
