产品名称
TRAF5 Rabbit Polyclonal Antibody
蛋白名称
TNF receptor-associated factor 5 (RING finger protein 84)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7188
Human Swissprot No.
O00463
Human Swissprot Link
https://www.uniprot.org/uniprot/O00463
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22033
Mouse Swissprot No.
P70191
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P70191/entry
特异性
This antibody detects endogenous levels of TRAF5 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
细胞定位
Cytoplasm . Cytoplasm, cytosol .
功能
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
