产品名称
PDE6B Rabbit Polyclonal Antibody
蛋白名称
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (GMP-PDE beta) (EC 3.1.4.35)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5158
Human Swissprot No.
P35913
Human Swissprot Link
https://www.uniprot.org/uniprot/P35913
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18587
Mouse Swissprot No.
P23440
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P23440/entry
特异性
This antibody detects endogenous levels of PDE6B at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Membrane; Lipid-anchor. Cell projection, cilium, photoreceptor outer segment .
功能
Rod-specific cGMP phosphodiesterase that catalyzes the hydrolysis of 3',5'-cyclic GMP . Necessary for the formation of a functional phosphodiesterase holoenzyme (By similarity). Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock (By similarity). May participate in processes of transmission and amplification of the visual signal .
