产品名称
SMYD3 Rabbit Polyclonal Antibody
基因名称
SMYD3 ZMYND1 ZNFN3A1
蛋白名称
SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64754
Human Swissprot No.
Q9H7B4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9H7B4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69726
Mouse Swissprot No.
Q9CWR2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWR2/entry
特异性
This antibody detects endogenous levels of SMYD3 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas.
细胞定位
Cytoplasm . Nucleus . Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M. .
功能
Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation . Also methylates 'Lys-5' of histone H4 . Plays an important role in transcriptional activation as a member of an RNA polymerase complex . Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences .
