产品名称
R51A1 Rabbit Polyclonal Antibody
蛋白名称
RAD51-associated protein 1 (RAD51-interacting protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96B01
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96B01/entry
Mouse Swissprot No.
Q8C551
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C551
免疫原
Synthesized peptide derived from human protein . at AA range: 90-170
特异性
R51A1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
组织表达
Highly expressed in testis and thymus (PubMed:9396801). Lower levels in colon and small intestine (PubMed:9396801). Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes (PubMed:9396801).
细胞定位
Chromosome . Nucleus . Chromosome, telomere . Colocalizes with RAD51 to multiple nuclear foci (By similarity). Colocalizes with DMC1 on meiotic chromatin (By similarity). .
功能
alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
