产品名称
WBP2 Rabbit Polyclonal Antibody
蛋白名称
WW domain-binding protein 2 (WBP-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23558
Human Swissprot No.
Q969T9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q969T9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22378
Mouse Swissprot No.
P97765
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P97765/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=192645
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R478/entry
特异性
This antibody detects endogenous levels of WBP2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
细胞定位
Cytoplasm . Nucleus . Translocates from cytoplasm to nucleus when phosphorylated. .
功能
Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation . In presence of estrogen, binds to ESR1-responsive promoters . Required for YAP1 coactivation function on PGR activity . Synergizes with WBP2 in enhancing PGR activity . Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity).
