产品名称
TIMM13 Rabbit Polyclonal Antibody
基因名称
TIMM13 TIM13B TIMM13A TIMM13B
蛋白名称
Mitochondrial import inner membrane translocase subunit Tim13
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26517
Human Swissprot No.
Q9Y5L4
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9Y5L4
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=30055
Mouse Swissprot No.
P62075
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P62075/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=252928
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P62076/entry
特异性
This antibody detects endogenous levels of TIMM13 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .
功能
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.
