产品名称
RINT1 Rabbit Polyclonal Antibody
蛋白名称
RAD50-interacting protein 1 (RAD50 interactor 1) (HsRINT-1) (RINT-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6NUQ1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6NUQ1/entry
Mouse Swissprot No.
Q8BZ36
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BZ36
免疫原
Synthesized peptide derived from human protein . at AA range: 550-630
特异性
RINT1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
developmental stage:Expressed throughout the cell cycle.,function:Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. May play a role in cell cycle checkpoint control. Essential for telomere length control.,miscellaneous:According to PubMed:11096100, a longer form, which may be due to the differential initiation of translation using a non-AUG codon, may exist. However, the existence of such form has not been clearly demonstrated.,similarity:Belongs to the RINT1 family.,similarity:Contains 1 RINT1/TIP20 domain.,subunit:Associated with a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L, and SEC22B. Interacts directly with BNIP1/SEC20L and ZW10. Interacts with RAD50 during late S and G2/M phases. Interacts with RBL2, preferentially with the active, hypophosphorylated form.,
组织表达
B-cell,Brain,Embryo,Testis,
细胞定位
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein.
功能
developmental stage:Expressed throughout the cell cycle.,function:Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. May play a role in cell cycle checkpoint control. Essential for telomere length control.,miscellaneous:According to PubMed:11096100, a longer form, which may be due to the differential initiation of translation using a non-AUG codon, may exist. However, the existence of such form has not been clearly demonstrated.,similarity:Belongs to the RINT1 family.,similarity:Contains 1 RINT1/TIP20 domain.,subunit:Associated with a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L, and SEC22B. Interacts directly with BNIP1/SEC20L and ZW10. Interacts with RAD50 during late S and G2/M phases. Interacts with RBL2, preferentially with the active, hypophosphorylated form.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
