产品名称
MXD1 Rabbit Polyclonal Antibody
蛋白名称
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4084
Human Swissprot No.
Q05195
Human Swissprot Link
https://www.uniprot.org/uniprot/Q05195
Mouse Swissprot No.
P50538
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P50538/entry
特异性
This antibody detects endogenous levels of MXD1 at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of a transcriptional repressor complex together with MAX . In complex with MAX binds to the core DNA sequence 5'-CAC[GA]TG-3' . Antagonizes MYC transcriptional activity by competing with MYC for MAX binding . Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding .