产品名称
Cingulin Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57530
Human Swissprot No.
Q9P2M7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9P2M7
Mouse Swissprot No.
P59242
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P59242/entry
特异性
This antibody detects endogenous levels of Cingulin at Human
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
细胞定位
Cell junction, tight junction . Localizes to the apical junction complex composed of tight and adherens junctions (By similarity). Colocalizes with SPEF1 at sites of cell-cell contact in intestinal epithelial cells (PubMed:12023291). .
功能
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
