产品名称
USP22 Rabbit Polyclonal Antibody
基因名称
USP22 KIAA1063 USP3L
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23326
Human Swissprot No.
Q9UPT9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9UPT9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=216825
Mouse Swissprot No.
Q5DU02
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5DU02/entry
特异性
This antibody detects endogenous levels of USP22 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver.
功能
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
