产品名称
DPEP1 Rabbit Polyclonal Antibody
蛋白名称
Dipeptidase 1 (EC 3.4.13.19) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1800
Human Swissprot No.
P16444
Human Swissprot Link
https://www.uniprot.org/uniprot/P16444
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13479
Mouse Swissprot No.
P31428
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P31428/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94199
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P31430/entry
特异性
This antibody detects endogenous levels of DPEP1 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in lung and kidneys.
细胞定位
Apical cell membrane ; Lipid-anchor, GPI-anchor . Cell projection, microvillus membrane ; Lipid-anchor, GPI-anchor . Brush border membrane. .
功能
Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 . Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (By similarity). Possesses also beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics . ; Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
