产品名称
LACTB Rabbit Polyclonal Antibody
基因名称
LACTB MRPL56 UNQ843/PRO1781
蛋白名称
Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114294
Human Swissprot No.
P83111
Human Swissprot Link
https://www.uniprot.org/uniprot/P83111
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80907
Mouse Swissprot No.
Q9EP89
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EP89/entry
特异性
This antibody detects endogenous levels of LACTB at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed predominantly in skeletal muscle.
功能
Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism . Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism . It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein . Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism .
