产品名称
INTS10 Rabbit Polyclonal Antibody
蛋白名称
Integrator complex subunit 10 (Int10)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55174
Human Swissprot No.
Q9NVR2
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9NVR2
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70885
Mouse Swissprot No.
Q8K2A7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K2A7/entry
特异性
This antibody detects endogenous levels of INTS10 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex .