产品名称
BTG2 Rabbit Polyclonal Antibody
蛋白名称
Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7832
Human Swissprot No.
P78543
Human Swissprot Link
https://www.uniprot.org/uniprot/P78543
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12227
Mouse Swissprot No.
Q04211
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q04211/entry
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29619
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P27049/entry
特异性
This antibody detects endogenous levels of BTG2 at Human, Mouse,Rat
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
功能
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
