产品名称
IFT43 Rabbit Polyclonal Antibody
蛋白名称
Intraflagellar transport protein 43 homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112752
Human Swissprot No.
Q96FT9
Human Swissprot Link
https://www.uniprot.org/uniprot/Q96FT9
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=76411
Mouse Swissprot No.
Q9DA69
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DA69/entry
特异性
This antibody detects endogenous levels of IFT43 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Expressed in the retina, predominantly in the photoreceptor outer segment.
细胞定位
Cytoplasm, cytoskeleton . Cell projection, cilium . Associated with microtubules (PubMed:22361696). Localized at the distal tip of the cilium (PubMed:28973684). .
功能
As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis . Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base .