产品名称
RBGP1 Rabbit Polyclonal Antibody
蛋白名称
Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y3P9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y3P9/entry
Mouse Swissprot No.
A2AWA9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/A2AWA9
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
RBGP1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Intron retention.,similarity:Contains 1 PID domain.,similarity:Contains 1 Rab-GAP TBC domain.,subcellular location:Predominantly cytosolic but also associated with the centrosome.,subunit:Interacts with RAB6A and tubulin gamma.,
组织表达
Brain,Mammary gland,Placenta,Testis,Umbilical cord blood,Uterus,
细胞定位
Cytoplasm, cytosol . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Predominantly cytosolic but also associated with the centrosome. .
功能
function:May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Intron retention.,similarity:Contains 1 PID domain.,similarity:Contains 1 Rab-GAP TBC domain.,subcellular location:Predominantly cytosolic but also associated with the centrosome.,subunit:Interacts with RAB6A and tubulin gamma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
