产品名称
BCO2 Rabbit Polyclonal Antibody
蛋白名称
Beta,beta-carotene 9',10'-oxygenase (EC 1.14.99.n2) (B-diox-II) (Beta-carotene dioxygenase 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83875
Human Swissprot No.
Q9BYV7
Human Swissprot Link
https://www.uniprot.org/uniprot/Q9BYV7
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170752
Mouse Swissprot No.
Q99NF1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99NF1/entry
特异性
This antibody detects endogenous levels of BCO2 at Human, Mouse
运输及保存条件
-15°C to -25°C/1 year(Do not lower than -25°C)
组织表达
Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level).
功能
Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules.
